A new diffusion metric, diffusion kurtosis imaging, used in the serial examination of a patient with stroke
نویسندگان
چکیده
WE REPORT A CASE OF A PATIENT WHO DEVELOPED A CEREBRAL INFARCTION, WHICH WAS ASSESSED USING A NEW AND ADVANCED DIFFUSION TECHNIQUE: diffusional kurtosis (DK) imaging. The signal changes on DK images were different from those on apparent diffusion coefficient (ADC) maps, and they seem to be useful for the prediction of early-stage tissue infarction. Although diffusion-weighted imaging and its metric, the ADC, have been widely used in the evaluation of stroke, DK imaging will provide additional and useful information, including a more detailed evaluation of pathologic tissue changes. This information can be predictive of the prognosis.
منابع مشابه
Diffusional Kurtosis Imaging in Acute Human Stroke
The management of acute human stroke is a high-priority medical emergency. Thrombolytic therapy is now part of the standard of care in most major medical centers, and the selection of patients for these treatments depends on several clinical factors as well as brain imaging findings. Diffusion MRI combined with perfusion imaging are accepted imaging protocols used to characterize ischemic strok...
متن کاملStratification of heterogeneous diffusion MRI ischemic lesion with kurtosis imaging: evaluation of mean diffusion and kurtosis MRI mismatch in an animal model of transient focal ischemia.
BACKGROUND AND PURPOSE Ischemic tissue damage is heterogeneous, resulting in complex patterns in the widely used diffusion-weighted MRI. Our study examined the spatiotemporal characteristics of diffusion kurtosis imaging in an animal model of transient middle cerebral artery occlusion. METHODS Adult male Wistar rats (N=18) were subjected to 90 minutes middle cerebral artery occlusion. Multipa...
متن کاملStroke assessment with diffusional kurtosis imaging.
BACKGROUND AND PURPOSE Despite being the gold standard technique for stroke assessment, conventional diffusion MRI provides only partial information about tissue microstructure. Diffusional kurtosis imaging is an advanced diffusion MRI method that yields, in addition to conventional diffusion information, the diffusional kurtosis, which may help improve characterization of tissue microstructure...
متن کاملDiffusional kurtosis and diffusion tensor imaging reveal different time-sensitive stroke-induced microstructural changes.
BACKGROUND AND PURPOSE Diffusion MRI is a promising, clinically feasible imaging technique commonly used to describe white matter changes after stroke. We investigated the sensitivity of diffusion MRI to detect microstructural alterations in gray matter after sensorimotor cortex stroke in adult male rats. METHODS The mean diffusivity (MD) and mean kurtosis of perilesional motor cortex were co...
متن کاملRole of Apparent diffusion coefficient value in Diffusion Weighted imaging of MRI to assessment of radiotherapy efficiency in the patient with glioma tumor during treatment
Introduction: Glioma is the most common primary malignancy of cerebral neoplasms in adults, which in spite of therapeutic significant efforts, has a very poor prognosis. The current standard treatment of these patients generally includes surgery and radiotherapy or concurrent chemoradiotherapy with 6 courses of adjuvant use of temozolomide tabs. During these years, the nervous...
متن کامل